Fig. 1
From: Celastrol promotes apoptotic cell death in thyroid cancer cells through a caspases-dependent pathway
Celastrol induces death in thyroid cancer cells. A-D Effect of Celastrol on the viability of human Thyroid cancer cells. Cells were challenged with increasing concentrations of Celastrol for 24h,48h,72h or 96h and cell viability was measured by CCK-8. IC50 values in different cell lines (KTC-1 and MDA-T32 (PTC), TT (MTC), and OCUT-2C (ATC)) are shown; E Colony formation assays: cells were treated with various doses of Celastrol for 24h and then allowed to grow for 10 days in fresh culture medium. Colonies were visualized by crystal purple staining; F Morphological alterations induced by Celastrol treatment