Fig. 4
From: Celastrol promotes apoptotic cell death in thyroid cancer cells through a caspases-dependent pathway
Celastrol suppressed tumor growth of ATC cells in vivo. A Original photo of tumor in tumor bearing mice under Celastrol treatment; B Tumor growth curve of tumor bearing mice under Celastrol treatment; C Performing HE and IHC staining on the transplant tumor (40X). D The IHC analysis revealed a significantly lower Ki-67 positivity rate in the Celastrol-treated group compared to the control group; D) The IHC analysis showed a significant increase in the cytoplasmic staining percentage of Caspase-3 in the tumor samples from the Celastrol-treated group compared to the control group